MyBioSource.com's NUDT1 antibody (clone AT3B3) is a Mouse monoclonal antibody. The NUDT1 antibody (clone AT3B3) was generated using nudix hydrolase 1, and NUDT1 as the antigen. It reacts with Human. This antibody has been shown to work in applications such as: ELISA, and Western Blot.
Description
Anti-human NUDT1 mAb, clone AT3B3, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human NUDT1 protein.
NUDT1, also known as MTH1 is a 179 amino acid cytoplasmic protein that is a member of the nudix hydrolase family. Highly expressed in testis, thymus and proliferating blood lymphocytes, NUDT1 functions as an antimutagenic that hydrolyzes oxidized purine nucleoside triphosphates to their corresponding monophosphates. Through its ability to enzymatically hydrolyze ATP and GTP to AMP and GMP, respectively, NUDT1 prevents misincorporation of GTP into DNA, thus preventing A:T to C:G transversions